2022年8月26日，The Plant Cell杂志在线发表了来自Paul E. Verslues等人题为“Burning questions for a warming and changing world: 15 unknowns in plant abiotic stress”的研究论文，该研究提出了植物非生物胁迫生物学中15个未解决的问题，这些问题由具有从生态生理学到细胞和分子生物学的专业知识的研究小组提出。
这些问题的共同主题包括需要更好地了解植物如何检测水的可用性、温度、盐度和不断上升的二氧化碳水平；环境信号如何与内源性信号和发育相互作用（例如生物钟、开花时间）；以及这种综合信号如何控制下游反应（例如气孔调节、脯氨酸代谢、生长与防御平衡）。质膜经常作为关键信号传导和转运事件（例如机械传感和脂质衍生信号传导、水通道蛋白）的位点出现。适应极端水和不断上升的二氧化碳会影响水力结构和蒸腾作用，以及根和枝条的生长和形态，其方式尚不完全清楚。环境适应涉及在不断变化和日益不可预测的环境中限制生态分布和作物恢复力的权衡。具体如下：
1. Can plasticity in traits beneficial in both wet and dry soils be recognized and used to limit crop yield loss? (By Julia Bailey-Serres)
2. How do plants sense and communicate water deficit? (By Alexander Christmann and Erwin Grill)
3. How, where, and when are water deficit signals integrated during floral transition? (By Lucio Conti)
4. How do we incorporate plant diversity into our molecular understanding of environmental stress adaptation? (By José R. Dinneny)
5. How do plants integrate climate signals? (By Scott Hayes and Christa Testerink)
6. How do trade-offs impact abiotic stress responses and climate adaptation? (By Robert W. Heckman and Thomas E. Juenger)
7. How does the circadian clock “gate” plant responses to abiotic stress? (By Paloma Mas)
8. How do lipid-derived second messengers translate abiotic stress information into cellular responses for stress acclimation? (By Teun Munnik)
9. How can laboratory stress research be applied to continuously stressed plants in the field? (By Hilde Nelissen)
10. Where is the plant most hydraulically vulnerable? (By Lawren Sack, Craig Brodersen, Thomas N. Buckley)
11. How Does the Continuing Rise in CO2 Affect the Regulation of Stomatal Apertures and Water Use Efficiency of Plants? (By Julian I. Schroeder and Po-Kai Hsu)
12. How can one aquaporin have so many roles in a plant? (By Stephen D. Tyerman)
13. How do plants balance growth and abiotic stress responses? (By Taishi Umezawa)
14.Proline Metabolism: Protector, Scavenger, or Executioner? (By Paul E. Verslues)
15.Temperature Sensing: How do plants adapt to different climates? (By Philip A. Wigge)
来源：Plant Cell
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