加拿大圣玛丽大学招收生物化学博士

加拿大圣玛丽大学招收生物化学博士

About the Project:

Falls among seniors are commonly linked with the sensation of dizziness and imbalance which is attributed to balance disorders. There is a persuasive medical hypothesis stating that balance disorders among the senior population are caused by otoconia degeneration. Otoconia are assemblies composed of highly organized crystalline and protein nanostructures. They are calcite-based, micron-sized biocrystals present in mammalian inner ears which are coupled to sensory hair cells, providing the sensation of balance and spatial orientation, critical for moving without falling.

We are looking for a highly motivated PhD candidate who is interested in using advanced laser microscopy techniques for investigating dissected otoconia from mice to advance our understanding of balance disorders with the overall goal of enhancing health care.

The project goals are (1) to learn how to dissect otoconia from the inner ears of mice, (2) to use a homebuilt nonlinear laser scanning microscope to image the otoconia, and (3) perform degradation experiments to the otoconia while imaging with the laser scanning microscope. Images taken during experiments will be analysed with a custom MATLAB fitting program.

Applicants with an interest in interdisciplinary research and a strong background in Biology, Chemistry, Physics or Engineering research are welcome to apply.

Please read about our research (publications) at the group website to learn more about our techniques and projects.

Please include the following items as an application file: (1) curriculum vitae, (2) copy of university transcript/diplomas, (3) contact details of two references and (4) a copy of documents confirming English proficiency if from outside Canada (TOEFL IBT, IELTS or IELTS etc.; please see accepted English language requirements for entry into academic programs at SMU at https://www.smu.ca/academics/graduate-studies-language-requirements.html).

Please, apply by email at danielle.tokarz@smu.ca

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