Postdoctoral positions are immediately available in Professor Guangxiang Luo’s lab in UAB
Postdoctoral positions are immediately available to determine the importance and underlying molecular mechanisms of viral and host interactions in the infection, replication, and morphogenesis of hepatitis B virus (HBV) and SARS-CoV-2 and their pathogenesis in vitro and in vivo. Other interesting research areas include innate immune evasion by SARS-CoV-2, HBV/HCV-induced hepatocellular carcinoma (HCC) particularly in hepatic cancer stem cells (CSCs), and antiviral and anti-cancer drug discovery.
Innovative research approaches developed in the lab include mouse models of HBV/HCV infection and replication, robust cell culture models of HBV/HCV/SARS-CoV-2 infections, genomics, proteomics, bioinformatics, gene-editing (CRISPR/Cas9) system, cell biological, gene-knockout and immunological technologies.
Candidates with research interests and experience in molecular virology, molecular biology, stem cell research, genome-wide profiling of transcriptome, genomics and proteomics, animal modeling of disease, and/or tumor biology are encouraged to apply. Salary and fringe benefits are highly competitive and commensurate with research experience.
Applicants with Ph.D., M.D., or equivalent degrees should send their CVs along with contact information of three referees to: Dr. George Luo at gluo@uab.edu. The Department of Microbiology, Center for AIDS Research (CFAR), and the Comprehensive Cancer Center at the University of Alabama at Birmingham (UAB) School of Medicine are national and international leaders in biomedical research.
UAB also offers an unusually interactive research environment with many other multidisciplinary centers, including Center for Structural Biology, Center for Clinical and Translational Sciences, Center for Emerging Infections and Emergency Preparedness, Liver Center, Transplant Institute, and campus-wide Program in Immunology. Birmingham and its surrounding areas are very attractive for single and family life with excellent school systems and affordable housing. UAB is an equal opportunity employer.
Recent publications:
Li Y, Luo G (2021) Human low-density lipoprotein receptor plays an important role in hepatitis B virus infection. PLoS Pathog 17(7):e1009722. https://doi.org/10.1371/journal. ppat.1009722.
Qiao L, Luo GG (2019) Human apolipoprotein E promotes hepatitis B virus infection and production. PLoS Pathog 15(8):e1007874. https://doi.org/10.1371/journal.ppat.1007874
阿拉巴马大学伯明翰医学院罗光湘教授实验室招聘博士后
美国阿拉巴马大学伯明翰医学院罗光湘教授实验室招聘博士后，实验室主要研究HBV、SARS-CoV-2等病毒与宿主的互作机制、体内外的致病机理。其他的研究方向还包括SARS-CoV-2的免疫逃逸、HBV/HCV诱导的肝细胞癌（尤其是肝癌干细胞），以及抗病毒药物和抗肿瘤药物的研发。
实验室的创新研究方法主要包括：支持HBV/HCV感染和复制的小鼠模型、HBV/HCV/SARS-CoV-2感染的稳定细胞培养模型、基因组学、蛋白质组学、生物信息学、基因编辑（CRISPR/Cas9）系统、细胞生物学、基因敲除和免疫学技术。
欢迎对分子病毒学、分子生物学、干细胞研究、转录组学分析、基因组学和蛋白质组学、疾病动物模型和/或肿瘤生物学领域感兴趣和拥有相关研究经验的候选人申请。实验室提供极具竞争力的薪酬及福利。
阿拉巴马大学伯明翰分校（University of Alabama at Birmingham，UAB）医学院的微生物学系、艾滋病研究中心（Center for AIDS Research，CFAR ）和综合癌症研究中心享誉世界，拥有包括结构生物学中心、临床和转化科学中心、新发感染和应急准备中心、肝脏研究所、移植研究所等多个科研机构。
罗光湘教授是阿拉巴马大学伯明翰医学院的讲席教授，在多个重要国际病原学期刊担任职务，包括Journal of Medical Virology的Deputy Editor、Plos Pathogens的Section Editor、Journal of Virology的Editorial Board Member等。欢迎感兴趣的申请人与罗光湘教授联系，邮箱：gluo@uab.edu.
近期文章:
Li Y, Luo G (2021) Human low-density lipoprotein receptor plays an important role in hepatitis B virus infection. PLoS Pathog 17(7):e1009722. https://doi.org/10.1371/journal. ppat.1009722.
Qiao L, Luo GG (2019) Human apolipoprotein E promotes hepatitis B virus infection and production. PLoS Pathog 15(8):e1007874. https://doi.org/10.1371/journal.ppat.1007874
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