2022/4/19 15:57:39 阅读：534 发布者：chichi77
Job description
Applications are invited for a 3 three-year position in a Research Fellowship as PhD Candidate in neuroscience at the Laboratory of Neural Development and Optical Recording (NDEVOR) at the Department of Molecular Medicine, University of Oslo, under the supervision of Professor Joel C. Glover. For the right candidate a four-year position, which also includes 25% teaching, supervision and/or administrative duties, may be possible. https://www.med.uio.no/imb/forskning/grupper/hjerneutvikling/index.html
More about the position
The PhD will be carried out as part of the project “Cracking the molecular code of brainstem-to-spinal cord neurons”, which aims to implement a single cell RNA sequencing analysis of this important set of neuron populations, and to develop from this information transgenic tools for selective functional manipulation of individual brainstem-to-spinal cord neuron groups using optogenetics and chemogenetics.
The PhD student will work within a research group focused generally on the development and function of descending inputs to the spinal cord in health and disease.
Specific tasks to be carried out by the PhD student will be some or all of the following: Selective labeling and isolation of brainstem-to-spinal cord neurons, preparation and implementation of single cell RNA sequencing, bioinformatics analysis of the RNAseq data in collaboration with Susan Dymecki’s group at Harvard University, advanced bioinformatics analysis in collaboration with Anthony Mathelier’s group at the Norwegian Center for Molecular Medicine, validation of putative molecular signatures using immunohistochemistry and spatial transcriptomics, and use of viral and murine transgenic tools to manipulate specific neuron groups in ex vivo preparations or freely moving mice.
Prior knowledge of brainstem-to-spinal cord neuron organization and function and experience in axonal tracing techniques, bioinformatics analysis, immunohistochemistry, and/or the use of transgenic mice and viral vectors will be considered positively in evaluating candidates.
The research fellow must take part in the Faculty’s approved PhD program and is expected to complete the project within the set fellowship period. The main purpose of the fellowship is research training leading to the successful completion of a PhD degree.
The applicant must, in collaboration with her/his supervisor, within three months after employment, have worked out a complete project description to be attached to the application for admission to the doctoral program. For more information, please see the web site.
Qualification requirements
-The candidate must hold a master’s degree/diploma (120 ECTS) level degree in neuroscience, molecular biology, or a medical degree with sufficient laboratory research experience. Minimum grade B (ECTS grading scale) or equivalent. The Master’s degree must include a thesis of at least 30 ECTS
-Strong laboratory, analytical, and communication skills
-Fluency in English
-Experience with some of the methods listed above will be considered an advantage
We offer
-Excellent working conditions
-An exciting and stimulating academic environment
-Salary NOK 491 200 – 534 400 per annum depending on qualifications in a position as PhD Research fellow (position code 1017)
-Attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities
How to apply
The application must include:
-cover letter statement of motivation and research interests
-CV (summarizing education, positions and academic work)
-copies of educational certificates (academic transcripts only)
-list of reference persons: 2-3 references (name, relation to candidate, e-mail and phone number)
-The application with attachments must be delivered in our electronic recruiting system, please follow the link “apply for this job”. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English (or a Scandinavian language).
-When evaluating the application, emphasis will be given to the applicant’s academic and personal prerequisites to carry out the project. Applicants may be called in for an interview.
Deadline 1st May 2022
https://www.jobbnorge.no/en/available-jobs/job/224124/phd-candidate-in-neuroscience
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