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JERP简讯 | 2022年6月刊速览(Volume 7, Issue 2)

2022/7/4 15:02:27  阅读:1008 发布者:

Journal of Exploratory Research in Pharmacology

2022625

Volume 7  Issue 2

正式出版

封面文章

Artificial synthetic NLRP3 modulators

人工合成的 NLRP3 调节剂

封面解读

Overall regulatory mechanisms for three artificial synthetic NLRP3 modulators: MCC950, EP, and ticagrelor on the activation of NLRP3 inflammasome.

CLICs, chloride intracellular channel proteins; TLR4, toll like receptor 4; HMGB1, high mobility group protein 1; NF-κB, nuclear factor kappa B; Nrf2, nuclear factor E2-related factor; ASC, apoptosis-associated speck-like protein containing a caspase recruitment domain.

三种人工合成 NLRP3 调节剂的总体调节机制:MCC950EP 和替格瑞洛对 NLRP3 炎性体激活的影响。

CLICs,氯化物细胞内通道蛋白;TLR4toll 样受体 4HMGB1,高迁移率族蛋白 1NF-κB,核因子 kappa BNrf2,核因子E2相关因子;ASC,含有半胱天冬酶募集结构域的凋亡相关斑点样蛋白。

Contents | 内容概览

本期共发表7篇文章:包括1Letter to the Editor4Original Article2Review Article

Letter to the Editor

Subclinical Hyperthyroidism is One of the Modifiable Risk Factors for Atrial Fibrillation

Milovan M. Stojanovic, Vidosava S. Stojanovic, Duska C. Stojanovic

Doi: 10.14218/JERP.2021.00054

Original Article

Formulation and Characterization of Lacosamide-loaded Polymeric Microneedles

Kadir Aykaç, Ebru Başaran

Doi: 10.14218/JERP.2021.00051

Original Article

Pre-clinical Exploratory Evaluation of Mab806-derived Immunotoxin in Targeting Solid Tumors with High Potency and Selectivity Towards EGFRvIII

Yan Zhang, Qiyu Qiu, Jing Xu, Hongyan Yang, Bing Sun

Doi: 10.14218/JERP.2022.00005

Original Article

Optimizing Ethanol Extraction of Rosemary Leaves and Their Biological Evaluations

Walid Yeddes, Hammami Majdi, Hamza Gadhoumi, Taycir Grati Affes, Salma Nait Mohamed, Wissem Aidi Wannes, Moufida Saidani-Tounsi

Doi: 10.14218/JERP.2022.00002

Original Article

Role of Hridayarnava Rasa on Erythrocyte Membrane Stabilization via Na+/K+ ATPase Activity in Atherosclerosis-induced Rabbits

Subramani Chitra, Rathinam Arunadevi, N. Gaidhani Sudesh, Raju Ilavarasan, Devi Veeraswamy Sharmila, K. Gautam Manish

Doi: 10.14218/JERP.2021.00041

Review Article

Application of NLRP3 Inflammasome-related Modulators in Sepsis

Ming-He Yang, Chu-Jun Duan, Shan-Shou Liu, Jian-Gang Xie

Doi: 10.14218/JERP.2021.00055

Review Article

Delivery System for Targeted Drug Therapy in Chronic Diseases

Yuan-Qi Jiang, Jin-Peng Chen, Yu-Jie Dong, Fu-Jun Zhou, Cheng-Wang Tian, Chang-Qing Chen

Doi: 10.14218/JERP.2021.00052

END

期刊简介

英文期刊Journal of Exploratory Research in Pharmacology (JERP, eISSN: 2572-5505)是华誉出版社(XHP, www.xiahepublishing.com)旗下药学研究期刊,于201611月正式创刊,侧重于药物在各治疗和应用领域的药理研究。

转自:华誉学术

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