Journal of Exploratory Research in Pharmacology
2022年6月25日
Volume 7 Issue 2
正式出版
封面文章
Artificial synthetic NLRP3 modulators
人工合成的 NLRP3 调节剂
封面解读
Overall regulatory mechanisms for three artificial synthetic NLRP3 modulators: MCC950, EP, and ticagrelor on the activation of NLRP3 inflammasome.
CLICs, chloride intracellular channel proteins; TLR4, toll like receptor 4; HMGB1, high mobility group protein 1; NF-κB, nuclear factor kappa B; Nrf2, nuclear factor E2-related factor; ASC, apoptosis-associated speck-like protein containing a caspase recruitment domain.
三种人工合成 NLRP3 调节剂的总体调节机制：MCC950、EP 和替格瑞洛对 NLRP3 炎性体激活的影响。
CLICs，氯化物细胞内通道蛋白；TLR4，toll 样受体 4；HMGB1，高迁移率族蛋白 1；NF-κB，核因子 kappa B；Nrf2，核因子E2相关因子；ASC，含有半胱天冬酶募集结构域的凋亡相关斑点样蛋白。
Contents | 内容概览
本期共发表7篇文章：包括1篇Letter to the Editor、4篇Original Article、2篇Review Article。
Letter to the Editor
Subclinical Hyperthyroidism is One of the Modifiable Risk Factors for Atrial Fibrillation
Milovan M. Stojanovic, Vidosava S. Stojanovic, Duska C. Stojanovic
Doi: 10.14218/JERP.2021.00054
Original Article
Formulation and Characterization of Lacosamide-loaded Polymeric Microneedles
Kadir Aykaç, Ebru Başaran
Doi: 10.14218/JERP.2021.00051
Original Article
Pre-clinical Exploratory Evaluation of Mab806-derived Immunotoxin in Targeting Solid Tumors with High Potency and Selectivity Towards EGFRvIII
Yan Zhang, Qiyu Qiu, Jing Xu, Hongyan Yang, Bing Sun
Doi: 10.14218/JERP.2022.00005
Original Article
Optimizing Ethanol Extraction of Rosemary Leaves and Their Biological Evaluations
Walid Yeddes, Hammami Majdi, Hamza Gadhoumi, Taycir Grati Affes, Salma Nait Mohamed, Wissem Aidi Wannes, Moufida Saidani-Tounsi
Doi: 10.14218/JERP.2022.00002
Original Article
Role of Hridayarnava Rasa on Erythrocyte Membrane Stabilization via Na+/K+ ATPase Activity in Atherosclerosis-induced Rabbits
Subramani Chitra, Rathinam Arunadevi, N. Gaidhani Sudesh, Raju Ilavarasan, Devi Veeraswamy Sharmila, K. Gautam Manish
Doi: 10.14218/JERP.2021.00041
Review Article
Application of NLRP3 Inflammasome-related Modulators in Sepsis
Ming-He Yang, Chu-Jun Duan, Shan-Shou Liu, Jian-Gang Xie
Doi: 10.14218/JERP.2021.00055
Review Article
Delivery System for Targeted Drug Therapy in Chronic Diseases
Yuan-Qi Jiang, Jin-Peng Chen, Yu-Jie Dong, Fu-Jun Zhou, Cheng-Wang Tian, Chang-Qing Chen
Doi: 10.14218/JERP.2021.00052
END
期刊简介
英文期刊Journal of Exploratory Research in Pharmacology (JERP, eISSN: 2572-5505)是华誉出版社（XHP, www.xiahepublishing.com）旗下药学研究期刊，于2016年11月正式创刊，侧重于药物在各治疗和应用领域的药理研究。
转自：华誉学术
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