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BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS《生物化学与生物物理学报:综合学科》 (官网投稿)

简介
  • 期刊简称BBA-GEN SUBJECTS
  • 参考译名《生物化学与生物物理学报:综合学科》
  • 核心类别 SCIE(2023版), 外文期刊,
  • IF影响因子
  • 自引率1.40%
  • 主要研究方向生物学-BIOCHEMISTRY & MOLECULAR BIOLOGY 生化与分子生物学;BIOPHYSICS 生物物理

主要研究方向:

等待设置主要研究方向
生物学-BIOCHEMISTRY & MOLECULAR BIOLOGY 生化与分子生物学;BIOPHYSICS 生物物理

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS《生物化学与生物物理学报:综合学科》(月刊). BBA General Subjects accepts for submission either original, hypothesis-driven s...[显示全部]
征稿信息

万维提示:

1、投稿方式:在线投稿。

2、期刊网址:

https://www.journals.elsevier.com/biochimica-et-biophysica-acta-general-subjects

3、投稿网址:

https://www.editorialmanager.com/bbagen/default.aspx

4、官网邮箱:bbagen@elsevier.com(编辑部)

5、期刊刊期:月刊,一年出版十二期。

2021414日星期三

                              

 

投稿须知【官网信息】

 

Guide for Authors

Your Paper Your Way

We now differentiate between the requirements for new and revised submissions. You may choose to submit your manuscript as a single Word or PDF file to be used in the refereeing process. Only when your paper is at the revision stage, will you be requested to put your paper in to a 'correct format' for acceptance and provide the items required for the publication of your article.

To find out more, please visit the Preparation section below.

BBA General Subjects accepts for submission either original, hypothesis-driven studies or reviews covering subjects in biochemistry and biophysics that have general scientific interest for a wide audience. Interdisciplinary studies are encouraged. Descriptive studies without biochemical or biophysical mechanistic evidence and insights are discouraged. Preferred topics are:

biomedicine: fundamental and emerging topics in biochemistry/biophysics with potential medical implications

nanobiology/nanotechnology: nanoparticles, nanotoxicology, nanomedicine

omics: genomics, proteomics, lipidomics, glycomics, bioinformatics addressing experimentally a defined biological question

chemical biology chemical compounds, drug mechanisms, synthesis of novel compounds, click chemistry

structural biology crystallography, NMR, multimeric proteins, protein dynamics, nucleic acids

novel complexes: nucleic acids, pure natural compounds, synthetic compounds, protein complexes, nucleic acid derivatives

cellular signaling: receptor signaling, protein phosphorylation cascades, phosphatases, secondary messengers, transcription regulation, gene expression

glycobiology: sugar metabolites and metabolism, glycosylated proteins, membrane protein, glycosylation, glycomics

redox biology: redox switches, glutathione and thioredoxin systems, oxygen and nitrogen radical species, superoxide, hydrogen peroxide, hydroxyl radical, nitric oxide, peroxides, hypoxia, redox regulation of transcription factors

neurobiology: neuronal growth factors and nerve signaling, glial cells, autonomic and central nervous systems

stem cells: differentiation, stem cell isolation and cultivation, growth factors

imaging methodologies

mechanistic characterization of compounds having biochemical importance and general interest (drug leads, toxicants, nutrients, metabolites). BBA General Subjects does not consider studies on the biological effects of crude extracts of natural sources unless the exact active molecules are identified, singularly characterized and evaluated.

Structural data

For papers describing structures of biological macromolecules, the atomic coordinates and the related experimental data (structure factor amplitudes/intensities and/or NMR restraints) must be deposited at a member site of the Worldwide Protein Data Bank (http://www.wwpdb.org): RCSB PDB (http://www.pdb.org), MSD-EBI (http://www.ebi.ac.uk/pdbe/ , PDBj (http://www.pdbj.org), or BMRB (http://www.bmrb.wisc.edu). Manuscripts must carry a statement that coordinates and structure factors (or NMR restraints) have been deposited in the Protein Data Bank. The accession number(s) must be cited in the manuscript at the end of the Materials and Methods section. Authors must agree to release the atomic coordinates and experimental data immediately upon publication.

It is increasingly common for coordinates to be deposited in the Protein Data Bank without an associated publication. Before submission to BBA, authors are expected to search the Protein Data Bank for related structures using one or more alignment programs and report the outcome. Prior deposition of related coordinates, without an associated publication, does not necessarily preclude publication in BBA. The primary criteria for publication of a structure in BBA are that it provides novel structural insights or important new functional and biological insights that are likely to be of general interest.

Types of paper

Full-length research articles (Regular paper), Review articles and Mini-reviews, brief reports (BBA Research Letters)

Reviews and Mini Reviews

Reviews and mini-reviews are typically commissioned by the Editors. All Review Articles should be authoritative, state-of-the-art accounts of the selected research field, be of high interest, balanced and accurate. Beyond summaries of important scientific developments and ideas, authors are encouraged to identify and discuss how the field may be impacted or develop in the future, including insights that may be of significance to the scientific community. All BBA Review Articles undergo rigorous and full peer review, in the same way as regular research papers, and publication cannot be guaranteed. The number of co-authors of review articles is limited to five and each author is expected to make a substantial contribution to the writing of the manuscript.

Unsolicited reviews will be considered only in exceptional cases. The prospective author should be a recognized expert in the field of the proposed article. When submitting an unsolicited review authors need to include the following additional information in the cover letter: a list of the author(s)' most recent publication contributions (up to 5) which are relevant to the field of the proposed review, an explanation of the current interest and significance to the broad readership of the journal, that is, compelling reasons why the review should be considered.

Reviews (full-length) should provide a comprehensive analysis on topics of broad interest to the journal's readership. Reviews should be thorough, sufficiently critical and accommodate different points of view. They should not be exhaustive compilations of previously published data, nor should they merely cover contributions from the author's own research. They should stand out from other recently published reviews on the same theme. Reviews are typically about 6,000 to 10,000 words in length (excluding References and Figure legends), include an Abstract that is no longer than 150 words, up to 100 references (should include Titles), and a minimum of three figures/illustrations. The number of co-authors of review articles is limited to 5

Mini-reviews are succinct, focused updates of the literature related to a question of current interest in the scientific community (typically from the last 2-3 years). Subjects covered in Mini-reviews are generally narrower, either in scope or depth, than those covered in full-length Reviews. They should highlight/analyse/discuss recent and important findings and include the author's viewpoint on how the subject relates to the current state of the field. The author's personal assessment and interpretation of the data and her/his indication of controversies, shortcomings and gaps in the present state of knowledge are highly desirable, but should be presented as such. Views of possible future developments and relevance and applicability to other fields or disciplines are encouraged. Mini-reviews are usually 2000 to 4000 words in length (excluding References and Figure legends), include up to 50 references (should include titles) and no more than 1-3 figures/illustrations. A Structured Abstract that is no longer than 150 words, sub-divided into subsections entitled: Background; Scope or Review; Major Conclusions and General Significance should also be included. References should be numbered throughout the text ( e.g. [23]) and should have full Titles in the Reference list. The number of co-authors of review articles is limited to 3.

BBA Research Letters

BBA Research Letters briefly report on original scientific observations that are either limited in scope or preliminary in nature. The findings should be timely and of high significance for the relevant field of research. With a focus on simple and succinct communication, BBA Research Letters contain a short abstract, main body and references and should not be divided into headings. They are limited to 1,500 words (not including figure legends or references) and no more than 1 key figure or table; the abstract should be presented in a bullet points format and should be limited to 100 words. The reference list should not exceed 15 entries, and up to 3 additional figures or tables may be included as supplemental materials.

Contact details for submission

Papers should be submitted using the BBA General Subjects online submission system, https://www.editorialmanager.com/bbagen/default.aspx. For questions on the submission and reviewing process, please contact the Editorial Office at bbagen@elsevier.com.

Ethics in publishing

Please see our information pages on Ethics in publishing and Ethical guidelines for journal publication.

Studies in humans and animals

If the work involves the use of human subjects, the author should ensure that the work described has been carried out in accordance with The Code of Ethics of the World Medical Association (Declaration of Helsinki) for experiments involving humans. The manuscript should be in line with the Recommendations for the Conduct, Reporting, Editing and Publication of Scholarly Work in Medical Journals and aim for the inclusion of representative human populations (sex, age and ethnicity) as per those recommendations. The terms sex and gender should be used correctly.

Authors should include a statement in the manuscript that informed consent was obtained for experimentation with human subjects. The privacy rights of human subjects must always be observed.

All animal experiments should comply with the ARRIVE guidelines and should be carried out in accordance with the U.K. Animals (Scientific Procedures) Act, 1986 and associated guidelines, EU Directive 2010/63/EU for animal experiments, or the National Institutes of Health guide for the care and use of Laboratory animals (NIH Publications No. 8023, revised 1978) and the authors should clearly indicate in the manuscript that such guidelines have been followed. The sex of animals must be indicated, and where appropriate, the influence (or association) of sex on the results of the study.

All authors must disclose any financial and personal relationships with other people or organizations that could inappropriately influence (bias) their work. Examples of potential conflicts of interest include employment, consultancies, stock ownership, honoraria, paid expert testimony, patent applications/registrations, and grants or other funding. Authors should complete the declaration of interest statement using https://www.elsevier.com/declaration-of-competing-interests and upload to the submission system at the Attach/Upload Files step. Note: Please do not convert the .docx template to another file type. Author signatures are not required. If there are no interests to declare, please choose: 'Declarations of interest: none' in the template. This statement will be published within the article if accepted. More information.

Declaration of interest

All authors must disclose any financial and personal relationships with other people or organizations that could inappropriately influence (bias) their work. Examples of potential competing interests include employment, consultancies, stock ownership, honoraria, paid expert testimony, patent applications/registrations, and grants or other funding. Authors must disclose any interests in two places: 1. A summary declaration of interest statement in the title page file (if double anonymized) or the manuscript file (if single anonymized). If there are no interests to declare then please state this: 'Declarations of interest: none'. This summary statement will be ultimately published if the article is accepted. 2. Detailed disclosures as part of a separate Declaration of Interest form, which forms part of the journal's official records. It is important for potential interests to be declared in both places and that the information matches. More information.

Submission declaration and verification

Submission of an article implies that the work described has not been published previously (except in the form of an abstract, a published lecture or academic thesis, see 'Multiple, redundant or concurrent publication' for more information), that it is not under consideration for publication elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted, it will not be published elsewhere in the same form, in English or in any other language, including electronically without the written consent of the copyright-holder. To verify originality, your article may be checked by the originality detection service Crossref Similarity Check.

Preprints

Please note that preprints can be shared anywhere at any time, in line with Elsevier's sharing policy. Sharing your preprints e.g. on a preprint server will not count as prior publication (see 'Multiple, redundant or concurrent publication' for more information).

Use of inclusive language

Inclusive language acknowledges diversity, conveys respect to all people, is sensitive to differences, and promotes equal opportunities. Content should make no assumptions about the beliefs or commitments of any reader; contain nothing which might imply that one individual is superior to another on the grounds of age, gender, race, ethnicity, culture, sexual orientation, disability or health condition; and use inclusive language throughout. Authors should ensure that writing is free from bias, stereotypes, slang, reference to dominant culture and/or cultural assumptions. We advise to seek gender neutrality by using plural nouns ("clinicians, patients/clients") as default/wherever possible to avoid using "he, she," or "he/she." We recommend avoiding the use of descriptors that refer to personal attributes such as age, gender, race, ethnicity, culture, sexual orientation, disability or health condition unless they are relevant and valid. These guidelines are meant as a point of reference to help identify appropriate language but are by no means exhaustive or definitive.

Author contributions

For transparency, we encourage authors to submit an author statement file outlining their individual contributions to the paper using the relevant CRediT roles: Conceptualization; Data curation; Formal analysis; Funding acquisition; Investigation; Methodology; Project administration; Resources; Software; Supervision; Validation; Visualization; Roles/Writing - original draft; Writing - review & editing. Authorship statements should be formatted with the names of authors first and CRediT role(s) following. More details and an example

Authorship

All authors should have made substantial contributions to all of the following: (1) the conception and design of the study, or acquisition of data, or analysis and interpretation of data, (2) drafting the article or revising it critically for important intellectual content, (3) final approval of the version to be submitted.

Changes to authorship

Authors are expected to consider carefully the list and order of authors before submitting their manuscript and provide the definitive list of authors at the time of the original submission. Any addition, deletion or rearrangement of author names in the authorship list should be made only before the manuscript has been accepted and only if approved by the journal Editor. To request such a change, the Editor must receive the following from the corresponding author: (a) the reason for the change in author list and (b) written confirmation (e-mail, letter) from all authors that they agree with the addition, removal or rearrangement. In the case of addition or removal of authors, this includes confirmation from the author being added or removed.

Only in exceptional circumstances will the Editor consider the addition, deletion or rearrangement of authors after the manuscript has been accepted. While the Editor considers the request, publication of the manuscript will be suspended. If the manuscript has already been published in an online issue, any requests approved by the Editor will result in a corrigendum.

Article transfer service

This journal is part of our Article Transfer Service. This means that if the Editor feels your article is more suitable in one of our other participating journals, then you may be asked to consider transferring the article to one of those. If you agree, your article will be transferred automatically on your behalf with no need to reformat. Please note that your article will be reviewed again by the new journal. More information.

Copyright

Upon acceptance of an article, authors will be asked to complete a 'Journal Publishing Agreement' (see more information on this). An e-mail will be sent to the corresponding author confirming receipt of the manuscript together with a 'Journal Publishing Agreement' form or a link to the online version of this agreement.

Subscribers may reproduce tables of contents or prepare lists of articles including abstracts for internal circulation within their institutions. Permission of the Publisher is required for resale or distribution outside the institution and for all other derivative works, including compilations and translations. If excerpts from other copyrighted works are included, the author(s) must obtain written permission from the copyright owners and credit the source(s) in the article. Elsevier has preprinted forms for use by authors in these cases.

For gold open access articles: Upon acceptance of an article, authors will be asked to complete a 'License Agreement' (more information). Permitted third party reuse of gold open access articles is determined by the author's choice of user license.

Author rights

As an author you (or your employer or institution) have certain rights to reuse your work. More information.

Elsevier supports responsible sharing

Find out how you can share your research published in Elsevier journals.

Role of the funding source

You are requested to identify who provided financial support for the conduct of the research and/or preparation of the article and to briefly describe the role of the sponsor(s), if any, in study design; in the collection, analysis and interpretation of data; in the writing of the report; and in the decision to submit the article for publication. If the funding source(s) had no such involvement then this should be stated.

Elsevier journals comply with current NIH public access policy

Open access

Please visit our Open Access page for more information.

Elsevier Researcher Academy

Researcher Academy is a free e-learning platform designed to support early and mid-career researchers throughout their research journey. The "Learn" environment at Researcher Academy offers several interactive modules, webinars, downloadable guides and resources to guide you through the process of writing for research and going through peer review. Feel free to use these free resources to improve your submission and navigate the publication process with ease.

Language (usage and editing services)

Please write your text in good English (American or British usage is accepted, but not a mixture of these). Authors who feel their English language manuscript may require editing to eliminate possible grammatical or spelling errors and to conform to correct scientific English may wish to use the English Language Editing service available from Elsevier's Author Services.

Submission

Our online submission system guides you stepwise through the process of entering your article details and uploading your files. The system converts your article files to a single PDF file used in the peer-review process. Editable files (e.g., Word, LaTeX) are required to typeset your article for final publication. All correspondence, including notification of the Editor's decision and requests for revision, is sent by e-mail.

Referees

During the submission process, you will be required to provide the names, addresses, and e-mail addresses of 4 potential referees, as well as a brief description of their expertise relevant to your manuscript. Suggested reviewers should be individuals qualified to evaluate the work you have submitted. The reviewers suggested may not be current, recent or extensive collaborators of yours, and cannot have been involved in the preparation of the manuscript. Please note that the editor retains the sole right to decide whether or not the suggested reviewers are used.

Authors may request exclusion of certain referees if conflicts of interest are anticipated. However, no more than 3 such names should be given. Entire groups or institutions cannot be specified for exclusion.

NEW SUBMISSIONS

Submission to this journal proceeds totally online and you will be guided stepwise through the creation and uploading of your files. The system automatically converts your files to a single PDF file, which is used in the peer-review process.

As part of the Your Paper Your Way service, you may choose to submit your manuscript as a single file to be used in the refereeing process. This can be a PDF file or a Word document, in any format or lay-out that can be used by referees to evaluate your manuscript. It should contain high enough quality figures for refereeing. If you prefer to do so, you may still provide all or some of the source files at the initial submission. Please note that individual figure files larger than 10 MB must be uploaded separately.

References

There are no strict requirements on reference formatting at submission. References can be in any style or format as long as the style is consistent. Where applicable, author(s) name(s), journal title/book title, chapter title/article title, year of publication, volume number/book chapter and the article number or pagination must be present. Use of DOI is highly encouraged. The reference style used by the journal will be applied to the accepted article by Elsevier at the proof stage. Note that missing data will be highlighted at proof stage for the author to correct.

Formatting requirements

There are no strict formatting requirements but all manuscripts must contain the essential elements needed to convey your manuscript, for example Abstract, Keywords, Introduction, Materials and Methods, Results, Conclusions, Artwork and Tables with Captions.

If your article includes any Videos and/or other Supplementary material, this should be included in your initial submission for peer review purposes.

Divide the article into clearly defined sections.

Please ensure your paper includes page numbers - this is an essential peer review requirement.

Figures and tables embedded in text

Please ensure the figures and the tables included in the single file are placed next to the relevant text in the manuscript, rather than at the bottom or the top of the file. The corresponding caption should be placed directly below the figure or table.

Peer review

This journal operates a single anonymized review process. All contributions will be initially assessed by the editor for suitability for the journal. Papers deemed suitable are then typically sent to a minimum of two independent expert reviewers to assess the scientific quality of the paper. The Editor is responsible for the final decision regarding acceptance or rejection of articles. The Editor's decision is final. Editors are not involved in decisions about papers which they have written themselves or have been written by family members or colleagues or which relate to products or services in which the editor has an interest. Any such submission is subject to all of the journal's usual procedures, with peer review handled independently of the relevant editor and their research groups. More information on types of peer review.

REVISED SUBMISSIONS

Use of word processing software

Regardless of the file format of the original submission, at revision you must provide us with an editable file of the entire article. Keep the layout of the text as simple as possible. Most formatting codes will be removed and replaced on processing the article. The electronic text should be prepared in a way very similar to that of conventional manuscripts (see also the Guide to Publishing with Elsevier). See also the section on Electronic artwork.

To avoid unnecessary errors you are strongly advised to use the 'spell-check' and 'grammar-check' functions of your word processor.

Article structure

Subdivision - numbered sections

Divide your article into clearly defined and numbered sections. Subsections should be numbered 1.1 (then 1.1.1, 1.1.2, ...), 1.2, etc. (the abstract is not included in section numbering). Use this numbering also for internal cross-referencing: do not just refer to 'the text'. Any subsection may be given a brief heading. Each heading should appear on its own separate line.

Introduction

State the objectives of the work and provide an adequate background, avoiding a detailed literature survey or a summary of the results.

Material and methods

Provide sufficient details to allow the work to be reproduced by an independent researcher. Methods that are already published should be summarized, and indicated by a reference. If quoting directly from a previously published method, use quotation marks and also cite the source. Any modifications to existing methods should also be described.

Key resources table

To enable reproducibility of the research, we encourage authors to submit a Key Resources Table, which helps make the resources clear to readers. The Key Resources Table highlights the genetically modified organisms and strains, cell lines, reagents and other resources essential to reproduce the results presented in a paper. More information is available here https://www.elsevier.com/authors/author-resources/key-resources-table

Results

Results should be clear and concise.

Discussion

This should explore the significance of the results of the work, not repeat them. A combined Results and Discussion section is often appropriate. Avoid extensive citations and discussion of published literature.

Conclusions

The main conclusions of the study may be presented in a short Conclusions section, which may stand alone or form a subsection of a Discussion or Results and Discussion section.

Appendices

If there is more than one appendix, they should be identified as A, B, etc. Formulae and equations in appendices should be given separate numbering: Eq. (A.1), Eq. (A.2), etc.; in a subsequent appendix, Eq. (B.1) and so on. Similarly for tables and figures: Table A.1; Fig. A.1, etc.

Essential title page information

Title. Concise and informative. Titles are often used in information-retrieval systems. Avoid abbreviations and formulae where possible.

Author names and affiliations. Please clearly indicate the given name(s) and family name(s) of each author and check that all names are accurately spelled. You can add your name between parentheses in your own script behind the English transliteration. Present the authors' affiliation addresses (where the actual work was done) below the names. Indicate all affiliations with a lower-case superscript letter immediately after the author's name and in front of the appropriate address. Provide the full postal address of each affiliation, including the country name and, if available, the e-mail address of each author.

Corresponding author. Clearly indicate who will handle correspondence at all stages of refereeing and publication, also post-publication. This responsibility includes answering any future queries about Methodology and Materials. Ensure that the e-mail address is given and that contact details are kept up to date by the corresponding author.

Present/permanent address. If an author has moved since the work described in the article was done, or was visiting at the time, a 'Present address' (or 'Permanent address') may be indicated as a footnote to that author's name. The address at which the author actually did the work must be retained as the main, affiliation address. Superscript Arabic numerals are used for such footnotes.

Highlights

Highlights are mandatory for this journal as they help increase the discoverability of your article via search engines. They consist of a short collection of bullet points that capture the novel results of your research as well as new methods that were used during the study (if any). Please have a look at the examples here: example Highlights.

Highlights should be submitted in a separate editable file in the online submission system. Please use 'Highlights' in the file name and include 3 to 5 bullet points (maximum 85 characters, including spaces, per bullet point).

Abstract

Page 2 of the typescript should be reserved for the Abstract which should have no more than 250 words. For Regular Articles, this should follow a structured format, sub-divided into subsections entitled "Background"; "Methods"; "Results"; "Conclusions" and "General Significance". Each subsection should be brief and informative, emphasizing those points that are unique to the paper. Review Articles should also contain a Structured Abstract, sub-divided into subsections entitled "Background"; "Scope of Review"; "Major Conclusions"; and "General Significance". Since summaries are increasingly used by abstracting services which will cut off after a fixed number of words, it is important not to exceed the maximum number of words and to avoid bibliographic references and non-standard abbreviations.

Graphical abstract

Although a graphical abstract is optional, its use is encouraged as it draws more attention to the online article. The graphical abstract should summarize the contents of the article in a concise, pictorial form designed to capture the attention of a wide readership. Graphical abstracts should be submitted as a separate file in the online submission system. Image size: Please provide an image with a minimum of 531 × 1328 pixels (h × w) or proportionally more. The image should be readable at a size of 5 × 13 cm using a regular screen resolution of 96 dpi. Preferred file types: TIFF, EPS, PDF or MS Office files. You can view Example Graphical Abstracts on our information site.

Authors can make use of Elsevier's Illustration Services to ensure the best presentation of their images and in accordance with all technical requirements.

Keywords

Immediately after the abstract, provide a maximum of 6 keywords, using American spelling and avoiding general and plural terms and multiple concepts (avoid, for example, 'and', 'of'). Be sparing with abbreviations: only abbreviations firmly established in the field may be eligible. These keywords will be used for indexing purposes.

Abbreviations

Define abbreviations that are not standard in this field in a footnote to be placed on the first page of the article. Such abbreviations that are unavoidable in the abstract must be defined at their first mention there, as well as in the footnote. Ensure consistency of abbreviations throughout the article.

Acknowledgements

Collate acknowledgements in a separate section at the end of the article before the references and do not, therefore, include them on the title page, as a footnote to the title or otherwise. List here those individuals who provided help during the research (e.g., providing language help, writing assistance or proof reading the article, etc.).

Formatting of funding sources

List funding sources in this standard way to facilitate compliance to funder's requirements:

Funding: This work was supported by the National Institutes of Health [grant numbers xxxx, yyyy]; the Bill & Melinda Gates Foundation, Seattle, WA [grant number zzzz]; and the United States Institutes of Peace [grant number aaaa].

It is not necessary to include detailed descriptions on the program or type of grants and awards. When funding is from a block grant or other resources available to a university, college, or other research institution, submit the name of the institute or organization that provided the funding.

If no funding has been provided for the research, please include the following sentence:

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Standards for Reporting Enzymology Data (STRENDA)

This journal follows the recommendations of the STRENDA (Standards for Reporting Enzymology Data) Commission of the Beilstein-Institut for the reporting of kinetic and equilibrium binding data. Detailed guidelines can be found at (http://www.strenda.org/documents.html) or in this pdf file.

All reports of kinetic and binding data must include a description of the identity of the catalytic or binding entity (enzyme, protein, nucleic acid or other molecule). This information should include the origin or source of the molecule, its purity, composition, and other characteristics such as post-translational modifications, mutations, and any modifications made to facilitate expression or purification. The assay methods and exact experimental conditions of the assay must be fully described if it is a new assay or provided as a reference to previously published work, with or without modifications. The temperature, pH and pressure (if other than atmospheric) of the assay must always be included, even if previously published. In instances where catalytic activity or binding cannot be detected, an estimate of the limit of detection based on the sensitivity and error analysis of the assay should be provided. Ambiguous terms such as "not detectable" should be avoided. A description of the software used for data analysis should be included along with calculated errors for all parameters.

First-order and second-order rate constants: see pdf for full instructions.

Math formulae

Please submit math equations as editable text and not as images. Present simple formulae in line with normal text where possible and use the solidus (/) instead of a horizontal line for small fractional terms, e.g., X/Y. In principle, variables are to be presented in italics. Powers of e are often more conveniently denoted by exp. Number consecutively any equations that have to be displayed separately from the text (if referred to explicitly in the text).

Footnotes

Footnotes should be used sparingly. Number them consecutively throughout the article. Many word processors build footnotes into the text, and this feature may be used. Should this not be the case, indicate the position of footnotes in the text and present the footnotes themselves separately at the end of the article.

Artwork

Image manipulation

While it is accepted that authors sometimes need to manipulate images for clarity, manipulation for purposes of deception or fraud will be seen as scientific ethical abuse and will be dealt with accordingly. For graphical images, this journal is applying the following policy: no specific feature within an image may be enhanced, obscured, moved, removed, or introduced. Adjustments of brightness, contrast, or color balance are acceptable as long as they are applied to the entire image and do not obscure or eliminate any information present in the original. Nonlinear adjustments (e.g. changes to gamma settings) must be disclosed in the figure legend.

Digital images in manuscripts nearing acceptance for publication may be scrutinized for any indication of improper manipulation. BBA General Subjects reserves the right to ask for original data or images and, if these are not satisfactory, we may decide not to accept the manuscript.

Electronic artwork

General points

Make sure you use uniform lettering and sizing of your original artwork.

Preferred fonts: Arial (or Helvetica), Times New Roman (or Times), Symbol, Courier.

Number the illustrations according to their sequence in the text.

Use a logical naming convention for your artwork files.

Indicate per figure if it is a single, 1.5 or 2-column fitting image.

For Word submissions only, you may still provide figures and their captions, and tables within a single file at the revision stage.

Please note that individual figure files larger than 10 MB must be provided in separate source files.

A detailed guide on electronic artwork is available.

You are urged to visit this site; some excerpts from the detailed information are given here.

Formats

Regardless of the application used, when your electronic artwork is finalized, please 'save as' or convert the images to one of the following formats (note the resolution requirements for line drawings, halftones, and line/halftone combinations given below):

EPS (or PDF): Vector drawings. Embed the font or save the text as 'graphics'.

TIFF (or JPG): Color or grayscale photographs (halftones): always use a minimum of 300 dpi.

TIFF (or JPG): Bitmapped line drawings: use a minimum of 1000 dpi.

TIFF (or JPG): Combinations bitmapped line/half-tone (color or grayscale): a minimum of 500 dpi is required.

Please do not:

Supply files that are optimized for screen use (e.g., GIF, BMP, PICT, WPG); the resolution is too low.

Supply files that are too low in resolution.

Submit graphics that are disproportionately large for the content.

Color artwork

Please make sure that artwork files are in an acceptable format (TIFF (or JPEG), EPS (or PDF) or MS Office files) and with the correct resolution. If, together with your accepted article, you submit usable color figures then Elsevier will ensure, at no additional charge, that these figures will appear in color online (e.g., ScienceDirect and other sites) in addition to color reproduction in print. Further information on the preparation of electronic artwork.

Figure captions

Ensure that each illustration has a caption. A caption should comprise a brief title (not on the figure itself) and a description of the illustration. Keep text in the illustrations themselves to a minimum but explain all symbols and abbreviations used.

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