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Toxicology in Vitro(研究方向:毒理学) (官网投稿)

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Toxicology in Vitro(月刊),创刊于1987年,出版国家为英国。杂志发表关于体外系统应用和使用的原始研究论文和评论,以评估或预测化学品的毒性作用并阐明其作用机制。这些体外技术包括利用细胞或组织培养物,分离的细胞,组织切片,亚细胞级分,转基因细胞培养物和来自转基因生物体的细胞,以及在计算机模型中。该杂志将着重于涉及开发和验证新的体外方法的调查,例如基于传统和计算机建模的毒性效应预测; 关于使...[显示全部]











Author Guidelines


Types of paper


The Journal's main purpose will be the publication of papers reporting and interpreting original toxicological research involving the application or development of in vitro techniques. Brief Communications (2,500 word limit) documenting important new findings warranting expeditious publication will also be considered, as will concise interpretative Reviews of toxicological topics of contemporary significance. Letters to the Editor will be limited to comments on contributions already published in the Journal; if a letter is accepted, a response (for simultaneous publication) will be invited from the authors of the original contribution. Toxicology in Vitro also welcomes Correspondence from the scientific community, especially as they relate to Hot Topics and Debates. These are handled directly by the Editor-in-Chief and may be accompanied by responses.


Submission checklist


You can use this list to carry out a final check of your submission before you send it to the journal for review. Please check the relevant section in this Guide for Authors for more details.


Ensure that the following items are present:


One author has been designated as the corresponding author with contact details:

E-mail address

Full postal address


All necessary files have been uploaded:


Include keywords

All figures (include relevant captions)

All tables (including titles, description, footnotes)

Ensure all figure and table citations in the text match the files provided

Indicate clearly if color should be used for any figures in print

Graphical Abstracts / Highlights files (where applicable)

Supplemental files (where applicable)


Further considerations

Manuscript has been 'spell checked' and 'grammar checked'

All references mentioned in the Reference List are cited in the text, and vice versa

Permission has been obtained for use of copyrighted material from other sources (including the Internet)

Relevant declarations of interest have been made

Journal policies detailed in this guide have been reviewed

Referee suggestions and contact details provided, based on journal requirements


This journal has an embargo period of 12 months.


Language (usage and editing services)

Please write your text in good English (American or British usage is accepted, but not a mixture of these). Authors who feel their English language manuscript may require editing to eliminate possible grammatical or spelling errors and to conform to correct scientific English may wish to use the English Language Editing service available from Elsevier's WebShop.




Submission to this journal proceeds totally online and you will be guided stepwise through the creation and uploading of your files. The system automatically converts source files to a single PDF file of the article, which is used in the peer-review process. Please note that even though manuscript source files are converted to PDF files at submission for the review process, these source files are needed for further processing after acceptance. All correspondence, including notification of the Editor's decision and requests for revision, takes place by e-mail removing the need for a paper trail.



Revised versions

The medium of submission for revised papers is electronic, through the Elsevier website (http://ees.elsevier.com/tiv). Figures should be submitted as original high quality files of a standard graphics program. Revised versions should be returned within 3 months of the first date of decision. Failure to do so will result in any resubmission being treated as a new version and will therefore carry a new date of receipt.




The Editors require submissions by the authors of the names and addresses of 4 potential reviewers for this submission. The institutional address and e-mail address are required. At least 2 of the referees should be from a different country to the corresponding author's. The Editors reserve the right to use these or other reviewers.




Use of word processing software

Regardless of the file format of the original submission, at revision you must provide us with an editable file of the entire article. Keep the layout of the text as simple as possible. Most formatting codes will be removed and replaced on processing the article. The electronic text should be prepared in a way very similar to that of conventional manuscripts (see also the Guide to Publishing with Elsevier). See also the section on Electronic artwork.

To avoid unnecessary errors you are strongly advised to use the 'spell-check' and 'grammar-check' functions of your word processor.


Manuscript Format


Manuscripts should be written in clear and concise English; incomprehensible submissions will be returned to authors for revision. All pages must be numbered, including the Title Page, which should carry the title of the paper, the surnames and initials of the authors, and the names and address of the institutions where the work was done (with the affiliation of each author clearly indicated). Titles consisting of declarative or interrogative sentences are not acceptable. Please do not add line numbering to your source file as this will be added automatically by the EES system upon building of the PDF.




Introduction: A concise and clear statement on the background, purposes and significance of the work.


Material and methods


Materials and Methods: A detailed description of the experimental design and of any new or improved methods. Well-established methods and techniques may be identified by reference only.




Results: Presented concisely with the aid of tables or figures where appropriate. Duplication between this section and the Discussion must be avoided.




Discussion: A succinct interpretation of the data. Extensive literature reviews and highly speculative comments are discouraged.


Essential title page information


Title. Concise and informative. Titles are often used in information-retrieval systems. Avoid abbreviations and formulae where possible.

Author names and affiliations. Where the family name may be ambiguous (e.g., a double name), please indicate this clearly. Each author's academic or professional qualifications should also be listed. Present the authors' affiliation addresses (where the actual work was done) below the names. Indicate all affiliations with a lower-case superscript letter immediately after the author's name and in front of the appropriate address. Provide the full postal address of each affiliation, including the country name, and, if available, the e-mail address of each author.

Corresponding author. Clearly indicate who will handle correspondence at all stages of refereeing and publication, also post-publication. Ensure that telephone and fax numbers (with country and area code) are provided in addition to the e-mail address and the complete postal address.

Present/permanent address. If an author has moved since the work described in the article was done, or was visiting at the time, a "Present address" (or "Permanent address") may be indicated as a footnote to that author's name. The address at which the author actually did the work must be retained as the main, affiliation address. Superscript Arabic numerals are used for such footnotes.




Abstract: A self-contained summary of the objectives, results and significance of the study, not exceeding 200 words. Uninformative sentences such as "the significance of the results is discussed" are not acceptable.


Graphical abstract

Although a graphical abstract is optional, its use is encouraged as it draws more attention to the online article. The graphical abstract should summarize the contents of the article in a concise, pictorial form designed to capture the attention of a wide readership. Graphical abstracts should be submitted as a separate file in the online submission system. Image size: Please provide an image with a minimum of 531 × 1328 pixels (h × w) or proportionally more. The image should be readable at a size of 5 × 13 cm using a regular screen resolution of 96 dpi. Preferred file types: TIFF, EPS, PDF or MS Office files. You can view Example Graphical Abstracts on our information site.

Authors can make use of Elsevier's Illustration and Enhancement service to ensure the best presentation of their images and in accordance with all technical requirements: Illustration Service.




Highlights are mandatory for this journal. They consist of a short collection of bullet points that convey the core findings of the article and should be submitted in a separate file in the online submission system. Please use 'Highlights' in the file name and include 3 to 5 bullet points (maximum 85 characters, including spaces, or, maximum 20 words per bullet point). See http://www.elsevier.com/highlights for examples.




Immediately after the abstract, provide a maximum of 6 keywords, using American spelling and avoiding general and plural terms and multiple concepts (avoid, for example, 'and', 'of'). Be sparing with abbreviations: only abbreviations firmly established in the field may be eligible. These keywords will be used for indexing purposes.




Abbreviations should be used sparingly. Define abbreviations that are not standard in this field in a footnote to be placed on the first page of the article. Such abbreviations that are unavoidable in the abstract must be defined at their first mention there, as well as in the footnote. Ensure consistency of abbreviations throughout the article.




Acknowledgements: Providing recognition of sources of funding and donations of materials, and including any thanks the authors may wish to accord for advisory, technical or other assistance, since authorship should be limited to those who have made a major contribution to the study and to the preparation of the paper. Authors are advised to obtain approval for the wording of any acknowledgement from those whose help is noted.

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